After 157 years (a long time for us New World Westcoasters) of business, the iconic Cliff House restaurant closed its doors at the end of 2020. The stretch of coastline where the Cliff House structure stands is controlled by the National Parks Dept. Given the building's perfect perch just above the Pacific Ocean, I can only assume that new tenants will be found by the Parks folk sooner rather than later. Unfortunately, many restaurants without the cachet of the Cliff House are gone from the city permanently.
Here is a rather exhaustive list of SF restaurant covid closures for your viewing 'pleasure'---